Botulax® appears as a lyophilized white powder in a colorless transparent vial and should turn into a colorless transparent liquid when mixed with a diluent, such as physiological saline.
Dosage & Administration:
For blepharospasm treatment, reconstituted Botulax® 50/100/200 (refer to Dilution Table) should be injected using a sterile 27-30 gauge needle without electromyographic guidance. The initial recommended dose ranges from 1.25 to 2.5 units (0.05 mL to 0.1 mL volume at each site). This is injected into specific areas around the eyes. Typically, you will see the initial effects within three days, with the peak effect occurring at one to two weeks post-treatment. The effects usually last for approximately three months, after which the procedure can be repeated. If the initial treatment's response is considered insufficient (lasting less than two months), the dose may be increased by up to two-fold. However, it is generally not beneficial to inject more than 5.0 units per site. Some tolerance may develop if treatments are administered more frequently than every three months, and long-lasting effects are rare. The total cumulative dose of Botulax® 50/100/200 in a 30-day period should not exceed 200 units.
Dilution Technique:
Before injection, reconstitute the freeze-dried Botulax® 50/100/200 with sterile normal saline without preservatives. The recommended diluent is 0.9% Sodium Chloride Injection. Draw the appropriate amount of diluent using the correct syringe size. To prevent denaturation of the drug, inject the diluent gently into the vial. If the diluent is not pulled into the vial due to a lack of vacuum, discard the vial. Note the date and time of reconstitution on the label. Reconstituted Botulax® 50/100/200 should be used within 24 hours after reconstitution and stored in a refrigerator (2-8°C) during this time. The reconstituted solution should be clear.
It is a peripheral-acting muscle relaxant. It is one of the best procedures for shaping the patient's facial lines and delaying the onset of aging. The most popular non-surgical cosmetic technique for both men and women. The anaerobic bacterium Clostridium botulinum produces the highly purified neurotoxic protein known as hemagglutinin complex utilizing advanced technology in accordance with approved global GMP standards, technical guidelines, and manufacturing conditions for biological substances. It delivers a quick, temporary treatment for facial wrinkles and clinical diseases like blepharospasm, pediatric cerebral palsy, and hyperhidrosis by relaxing the muscles into which it has been injected.
Areas of application:
Neck and face
Indication:
Muscular activity leading to asymmetry in the face
Crow’s feet
Neck wrinkles
Nasolabial folds
Wrinkles between the eyebrows and forehead
Lip contour
Hyperhidrosis
Strengths:
Long-lasting, persistent therapeutic impact
Quicker results
Excellent tolerance for patients
Minimal discomfort with the injection process
The preservation of natural facial expressions while ensuring that all facial wrinkles are completely removed is determined by selective corrective activity.
The medicine, produced in 23 countries under a variety of commercial brands, is well-known around the world.
It has natural results
Effects:
After 3–7 days, the cosmetic effects are visible.
The impact lasts for around 6 to 9 months.
Typically, 2-3 treatments are required each year because muscle tone gradually restores.
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