BOTULAX 100 Units Overview
BOTULAX is a muscle relaxant containing purified botulinum toxin type A combined with haemagglutinin and sodium chloride. Its mechanism of action involves blocking nerve impulses, disrupting acetylcholine synthesis, and temporarily paralyzing facial muscles to smooth wrinkles.
Active Ingredient:
- Clostridium botulinum toxin type A
- Strain: Clostridium botulinum CBFC26
- Dose: 100 units (U)
Mode of Action:
- Type A botulinum toxin inhibits nerve signals to muscles, reducing their ability to contract and thereby minimizing wrinkles.
- Used for forehead lines, crow's feet, lion's wrinkles, and horizontal and vertical neck wrinkles, as well as for lip contour correction.
Effectiveness:
- BOTULAX 100 IU ensures high effectiveness with a controlled potency range of 91-115 units.
- It delivers precise and consistent results, ensuring high patient satisfaction.
- Packaged in a pressure-sealed glass ampoule, the powder requires reconstitution with saline before use (2.5 ml for 100 units, 5 ml for 200 units).
For blepharospasm treatment, reconstituted Botulax® 50/100/200 (refer to Dilution Table) should be injected using a sterile 27-30 gauge needle without electromyographic guidance. The initial recommended dose ranges from 1.25 to 2.5 units (0.05 mL to 0.1 mL volume at each site). This is injected into specific areas around the eyes. Typically, you will see the initial effects within three days, with the peak effect occurring at one to two weeks post-treatment. The effects usually last for approximately three months, after which the procedure can be repeated. If the initial treatment's response is considered insufficient (lasting less than two months), the dose may be increased by up to two-fold. However, it is generally not beneficial to inject more than 5.0 units per site. Some tolerance may develop if treatments are administered more frequently than every three months, and long-lasting effects are rare. The total cumulative dose of Botulax® 50/100/200 in a 30-day period should not exceed 200 units.
Areas of application:
Neck and face
Indication:
Muscular activity leading to asymmetry in the face
Crow’s feet
Neck wrinkles
Nasolabial folds
Wrinkles between the eyebrows and forehead
Lip contour
Hyperhidrosis
Strengths:
Long-lasting, persistent therapeutic impact
Quicker results
Excellent tolerance for patients
Minimal discomfort with the injection process
The preservation of natural facial expressions while ensuring that all facial wrinkles are completely removed is determined by selective corrective activity.
Effects:
After 3–7 days, the cosmetic effects are visible.
The impact lasts for around 6 to 9 months.
Typically, 2-3 treatments are required each year because muscle tone gradually restores.
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